Insulin Glargine Injection

Type 1 diabetes mellitus (lifelong), type 2 diabetes requiring insulin, gestational diabetes and diabetic ketoacidosis (soluble insulin, hospital setting).

Subcutaneous injection into the abdomen, thigh or upper arm, rotating injection sites; soluble insulin may also be given intravenously under medical supervision. Store at 2–8 °C, never freeze; in-use cartridges may be kept at room temperature for up to 28 days.

Individualised according to blood glucose, diet and activity. Typical adult requirement 0.5–1 unit/kg/day, given as twice-daily premixed or basal-plus-meal regimens. Adjust in illness, exercise and renal impairment. Monitor blood glucose regularly.

Main risk is hypoglycaemia — recognise sweating, tremor, hunger and confusion; carry glucose at all times. Educate on sick-day rules and injection-site rotation (lipohypertrophy). Do not change the product or regimen without medical advice.